21175

• Gene Symbol: EXOSC2
• Gene Name: exosome component 2
• Gene Aliases: RRP4, Rrp4p, hRrp4p, p7
• Chromosome Location: Chr.9: 130693760 - 130704894 on Build GRCh38
• UniGene ID: Hs.654643
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EXOSC2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001282709.1	NP_001269638.1	5	426
	NM_014285.6	NP_055100.2	6	516
	XM_005272176.2	XP_005272233.1	6	514
	XM_006717023.2	XP_006717086.1	5	424
	XM_017014558.1	XP_016870047.1	5	1048
GenBank mRNA	AK001916.1	-	6	505
	AK022460.1	-	6	502
	AK090512.1	-	5	1048
	AK092727.1	-	1	84
	BC000747.2	-	6	486	2821702
	DA813307.1	-	5	406

More Information

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
positive regulation of cell growth
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
U4 snRNA 3'-end processing
regulation of mRNA stability
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
CUT catabolic process
nuclear polyadenylation-dependent rRNA catabolic process
nuclear polyadenylation-dependent tRNA catabolic process
nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription
polyadenylation-dependent snoRNA 3'-end processing

Function(s)

3'-5'-exoribonuclease activity
exoribonuclease activity
protein binding
7S RNA binding