212727

• Gene Symbol: PDGFRB
• Gene Name: platelet derived growth factor receptor beta
• Gene Aliases: CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT
• Chromosome Location: Chr.5: 150113839 - 150155884 on Build GRCh38
• UniGene ID: Hs.509067
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PDGFRB
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002609.3	NP_002600.1	3	600
	XM_005268464.2	XP_005268521.1	2	579
	XM_011537658.1	XP_011535960.1	3	175
	XM_011537659.1	XP_011535961.1	4	1080
GenBank mRNA	AB209657.1	-	3	600
	AK293093.1	-	3	436
	BC032224.1	-	3	606	5309813
	EU826595.1	-	2	131
	J03278.1	-	3	487
	M21616.1	-	3	317

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
glycosaminoglycan biosynthetic process
signal transduction
G-protein coupled receptor signaling pathway
positive regulation of cell proliferation
response to toxic substance
positive regulation of phospholipase C activity
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of phosphatidylinositol 3-kinase signaling
positive regulation of smooth muscle cell migration
cell migration
peptidyl-tyrosine phosphorylation
positive regulation of cell migration
response to estradiol
positive regulation of phosphoprotein phosphatase activity
response to retinoic acid
regulation of actin cytoskeleton organization
positive regulation of collagen biosynthetic process
response to fluid shear stress
cell migration involved in vasculogenesis
metanephric mesenchymal cell migration
platelet-derived growth factor receptor-beta signaling pathway
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
aorta morphogenesis
cellular response to platelet-derived growth factor stimulus
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
wound healing
response to hydrogen peroxide
negative regulation of apoptotic process
positive regulation of MAP kinase activity
positive regulation of GTPase activity
positive regulation of phosphatidylinositol 3-kinase activity
response to estrogen
positive regulation of mitotic nuclear division
phosphatidylinositol metabolic process
protein autophosphorylation
phosphatidylinositol phosphorylation
platelet-derived growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
positive regulation of smooth muscle cell proliferation
inner ear development
positive regulation of chemotaxis
cardiac myofibril assembly
response to hyperoxia
cell chemotaxis
cell migration involved in coronary angiogenesis
retina vasculature development in camera-type eye
positive regulation of ERK1 and ERK2 cascade
smooth muscle cell chemotaxis
metanephric mesenchyme development
metanephric glomerular mesangial cell proliferation involved in metanephros development
metanephric glomerular capillary formation
metanephric comma-shaped body morphogenesis
metanephric S-shaped body morphogenesis
positive regulation of calcium ion import
positive regulation of reactive oxygen species metabolic process
positive regulation of DNA biosynthetic process

Function(s)

protein tyrosine kinase activity
platelet activating factor receptor activity
platelet-derived growth factor-activated receptor activity
platelet-derived growth factor beta-receptor activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
platelet-derived growth factor receptor binding
protein binding
ATP binding
protein kinase binding
vascular endothelial growth factor binding
phosphatidylinositol 3-kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
platelet-derived growth factor binding