212757

• Gene Symbol: LONP1
• Gene Name: lon peptidase 1, mitochondrial
• Gene Aliases: CODASS, LON, LONP, LonHS, PIM1, PRSS15, hLON
• Chromosome Location: Chr.19: 5691834 - 5720452 on Build GRCh38
• UniGene ID: Hs.350265
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: LONP1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001276479.1	NP_001263408.1	9	1043
	NM_001276480.1	NP_001263409.1	8	1007
	NM_004793.3	NP_004784.2	8	1328
	NR_076392.1		9	1026
	XM_011528441.2	XP_011526743.1	8	1371
GenBank mRNA	AK056366.1	-	8	1007
	AK096433.1	-	9	1056
	AK096626.1	-	9	1043
	AK127867.1	-	9	1108
	AK298531.1	-	9	1007
	AK309720.1	-	9	1216
	AL096720.1	-	7	642
	BC000235.1	-	8	1207	3350958
	BC109218.1	-	8	870
	BC139726.1	-	5	547
	U02389.1	-	8	1304

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_133404, AB064323.

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

mitochondrial genome maintenance
response to hypoxia
misfolded or incompletely synthesized protein catabolic process
mitochondrion organization
aging
response to hormone
response to aluminum ion
mitochondrial DNA metabolic process
cellular response to oxidative stress
chaperone-mediated protein complex assembly
protein homooligomerization
proteolysis involved in cellular protein catabolic process
oxidation-dependent protein catabolic process
regulation of mitochondrial DNA replication

Function(s)

single-stranded DNA binding
single-stranded RNA binding
ATP-dependent peptidase activity
serine-type endopeptidase activity
protein binding
ATP binding
ADP binding
sequence-specific DNA binding
G-quadruplex DNA binding
DNA polymerase binding
mitochondrial light strand promoter anti-sense binding
mitochondrial heavy strand promoter anti-sense binding
mitochondrial light strand promoter sense binding
mitochondrial heavy strand promoter sense binding