213391

• Gene Symbol: CHEK1
• Gene Name: checkpoint kinase 1
• Gene Aliases: CHK1
• Chromosome Location: Chr.11: 125624910 - 125676259 on Build GRCh38
• UniGene ID: Hs.24529
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CHEK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001114121.2	NP_001107593.1	10	1943
	NM_001114122.2	NP_001107594.1	10	1943
	NM_001244846.1	NP_001231775.1	10	1943
	NM_001274.5	NP_001265.2	10	1286
	NR_045204.1		9	1719
	NR_045205.1		10	1480
	XM_011542560.2	XP_011540862.1	9	1945
	XM_011542561.2	XP_011540863.1	9	1945
	XM_011542562.2	XP_011540864.1	9	1195
	XM_011542563.2	XP_011540865.1	9	1260
	XM_017017146.1	XP_016872635.1	10	1130
GenBank mRNA	AB451222.1	-	9	1046
	AB451345.1	-	9	1046
	AF016582.1	-	9	1080
	AF032874.1	-	9	1046
	AK292549.1	-	10	1480
	AK293143.1	-	10	1108
	AK299783.1	-	9	880
	AK300082.1	-	9	1129
	BC004202.2	-	10	1105	3530606
	BC017575.1	-	10	1204	4091997
	JF289264.1	-	9	921

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
G2/M transition of mitotic cell cycle
DNA replication
DNA repair
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
regulation of double-strand break repair via homologous recombination
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
peptidyl-threonine phosphorylation
G2 DNA damage checkpoint
histone H3-T11 phosphorylation
regulation of cell proliferation
negative regulation of mitotic nuclear division
regulation of mitotic centrosome separation
chromatin-mediated maintenance of transcription
cellular response to mechanical stimulus
replicative senescence
regulation of signal transduction by p53 class mediator
regulation of histone H3-K9 acetylation

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
histone kinase activity (H3-T11 specific)