213486

• Gene Symbol: KMT2D
• Gene Name: lysine methyltransferase 2D
• Gene Aliases: AAD10, ALR, CAGL114, KABUK1, KMS, MLL2, MLL4, TNRC21
• Chromosome Location: Chr.12: 49018975 - 49060884 on Build GRCh38
• UniGene ID: Hs.731384
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: KMT2D
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003482.3	NP_003473.3	31	6978
	XM_005269162.4	XP_005269219.1	32	8257
	XM_006719614.3	XP_006719677.1	32	8266
	XM_006719616.3	XP_006719679.1	32	8254
	XM_011538770.2	XP_011537072.1	32	8269
	XM_011538771.2	XP_011537073.1	32	8266
	XM_011538772.2	XP_011537074.1	32	8260
	XM_011538773.2	XP_011537075.1	32	8257
	XM_011538774.2	XP_011537076.1	32	8249
	XM_011538776.2	XP_011537078.1	32	8176
GenBank mRNA	AF010403.1	-	31	6153
	AF010404.1	-	22	5238

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008765859, XM_006257392, XM_006257393, XM_006257397, XM_006257396, and others.
This siRNA also targets the following transcripts in Mouse: NM_001033276.

Gene Ontology Categories:

Process(es)

oocyte growth
chromatin silencing
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of cell proliferation
positive regulation of intracellular estrogen receptor signaling pathway
response to estrogen
positive regulation of transcription from RNA polymerase II promoter
oogenesis
histone H3-K4 methylation
beta-catenin-TCF complex assembly

Function(s)

DNA binding
protein binding
zinc ion binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
transcription regulatory region DNA binding