214013

Gene Symbol:

AURKA AURKAPS1 VWA2

Gene Name:

aurora kinase A

aurora kinase A pseudogene 1

von Willebrand factor A domain containing 2

Gene Aliases:

AIK, ARK1, AURA, BTAK, PPP1R47, STK15, STK6, STK7

AurAps1, STK6P

AMACO, CCSP-2, NET42

Chromosome Location:

Chr.20: 56369389 - 56392337 on Build GRCh38

Chromosome Location:

Chr.1: 220266179 - 220267715 on Build GRCh38

Chromosome Location:

Chr.10: 114239254 - 114294500 on Build GRCh38

UniGene ID:

Hs.250822

Hs.654849

Hs.197741

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: AURKA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001323303.1	NP_001310232.1	10	1630
	NM_001323304.1	NP_001310233.1	10	1393
	NM_001323305.1	NP_001310234.1	11	1503
	NM_003600.3	NP_003591.2	9	1520
	NM_198433.2	NP_940835.1	11	1728
	NM_198434.2	NP_940836.1	10	1419
	NM_198435.2	NP_940837.1	9	1309
	NM_198436.2	NP_940838.1	10	1405
	NM_198437.2	NP_940839.1	9	1295
	XM_017028034.1	XP_016883523.1	11	1850
	XM_017028035.1	XP_016883524.1	9	1210
GenBank mRNA	AF008551.1	-	8	1120
	AF011468.1	-	9	1376
	AK301769.1	-	9	982
	AK312776.1	-	9	1187
	BC001280.1	-	10	1252	3456017
	BC002499.2	-	9	1248	3051177
	BC006423.1	-	9	1145	3532438
	BC027464.1	-	10	1287	4449474
	D84212.1	-	10	1286

Gene Symbol: AURKAPS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_001587.1		1	920

Gene Symbol: VWA2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_011539757.2	XP_011538059.1	1	99

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, extracellular matrix structural protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
meiotic spindle organization
protein phosphorylation
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
spindle organization
mitotic spindle organization
spindle assembly involved in female meiosis I
mitotic nuclear division
mitotic centrosome separation
anterior/posterior axis specification
anaphase-promoting complex-dependent catabolic process
regulation of protein stability
negative regulation of protein binding
response to estradiol
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of cytokinesis
histone-serine phosphorylation
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
positive regulation of mitotic nuclear division
regulation of centrosome cycle
protein autophosphorylation
cell division
centrosome localization
protein localization to centrosome
positive regulation of oocyte maturation
regulation of signal transduction by p53 class mediator
neuron projection extension
calcium-independent cell-matrix adhesion
regulation of insulin receptor signaling pathway
protein homooligomerization

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein binding
ATP binding
protein kinase binding
ubiquitin protein ligase binding
histone serine kinase activity
calcium ion binding
identical protein binding