214848

Gene Symbol:

RTEL1 RTEL1-TNFRSF6B

Gene Name:

regulator of telomere elongation helicase 1

RTEL1-TNFRSF6B readthrough (NMD candidate)

Gene Aliases:

C20orf41, DKCA4, DKCB5, NHL, PFBMFT3, RTEL

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Chromosome Location:

Chr.20: 63657810 - 63696253 on Build GRCh38

Chromosome Location:

Chr.20: 63657810 - 63698698 on Build GRCh38

UniGene ID:

Hs.745057

Hs.745057

Species:

Human

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: RTEL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001283009.1	NP_001269938.1	32	4088
	NM_001283010.1	NP_001269939.1	31	3809
	NM_016434.3	NP_057518.1	32	4088
	NM_032957.4	NP_116575.3	32	4160
GenBank mRNA	AF217795.1	-	32	4088
	AK000485.1	-	8	1291
	AK302508.1	-	32	3679
	AK304798.1	-	31	3305
	AL080127.1	-	9	1194
	JX119186.1	-	31	3261

Gene Symbol: RTEL1-TNFRSF6B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_037882.1		32	4088

More Information

Panther Classification:

Molecular Function -

DNA helicase

Gene Ontology Categories:

Process(es)

telomere maintenance
strand displacement
DNA repair
regulation of double-strand break repair via homologous recombination
replication fork processing
positive regulation of telomere maintenance
DNA duplex unwinding
telomere maintenance in response to DNA damage
telomeric loop disassembly
mitotic telomere maintenance via semi-conservative replication
positive regulation of telomere capping
positive regulation of telomere maintenance via telomere lengthening
negative regulation of t-circle formation
negative regulation of telomere maintenance in response to DNA damage
positive regulation of telomeric loop disassembly

Function(s)

DNA binding
ATP-dependent DNA helicase activity
protein binding
ATP binding
metal ion binding
4 iron, 4 sulfur cluster binding