21597

Gene Symbol:

RABGEF1 GS1-124K5.11

Gene Name:

RAB guanine nucleotide exchange factor 1

RAB guanine nucleotide exchange factor 1 pseudogene

Gene Aliases:

RABEX5, RAP1, rabex-5

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Chromosome Location:

Chr.7: 66682091 - 66811464 on Build GRCh38

Chromosome Location:

Chr.7: 66530305 - 66592407 on Build GRCh38

UniGene ID:

Hs.530053

Hs.732409

Species:

Human

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: RABGEF1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001287061.1	NP_001273990.1	3	550
	NM_001287062.1	NP_001273991.1	4	686
	NM_014504.2	NP_055319.1	3	491
GenBank mRNA	AJ250042.1	-	3	414
	AK223329.1	-	3	414
	AK290678.1	-	4	609
	AK303006.1	-	3	547
	BC015330.1	-	3	437	4420279
	BT007107.1	-	2	337
	DA196847.1	-	3	491
	DQ230533.1	-	2	337
	DQ230534.1	-	3	457

Gene Symbol: GS1-124K5.11
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_111974.1		2	308
	NR_111976.1		3	486
	NR_111979.1		3	483
GenBank mRNA	AK296922.1	-	5	656
	AK310370.1	-	2	285

More Information

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
negative regulation of leukocyte migration
protein targeting to membrane
endocytosis
protein ubiquitination
negative regulation of mast cell degranulation
positive regulation of GTPase activity
negative regulation of Ras protein signal transduction
negative regulation of receptor-mediated endocytosis
negative regulation of inflammatory response
regulation of Fc receptor mediated stimulatory signaling pathway
negative regulation of interleukin-6 secretion
negative regulation of Kit signaling pathway

Function(s)

DNA binding
protein binding
zinc ion binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
ubiquitin protein ligase activity