217145

• Gene Symbol: HLA-E
• Gene Name: major histocompatibility complex, class I, E
• Gene Aliases: EA1.2, EA2.1, HLA-6.2, MHC, QA1
• Chromosome Location: Chr.6: 30489406 - 30494205 on Build GRCh38
• UniGene ID: Hs.650174
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HLA-E
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005516.5	NP_005507.3	3	563
	XM_017010807.1	XP_016866296.1	2	575
	XM_017010808.1	XP_016866297.1	2	575
	XM_017010809.1	XP_016866298.1	3	460
GenBank mRNA	AB209870.1	-	3	430
	AJ293263.1	-	3	437
	AJ293264.1	-	3	437
	AK098434.1	-	3	460
	AK225048.1	-	3	457
	AK292391.1	-	3	515
	AK296822.1	-	2	587
	AK298695.1	-	3	457
	AK300906.1	-	3	383
	AK301125.1	-	3	238
	AK316327.1	-	3	388
	AY216681.1	-	3	437
	AY221103.1	-	3	437
	BC002578.2	-	3	451	3140835
	BC004297.1	-	3	435
	BC040479.1	-	3	457	4696327
	BM791769.1	-	3	502
	BX538084.1	-	2	355
	DA832616.1	-	3	563
	L78455.1	-	2	374
	L78934.1	-	2	373
	M20022.1	-	3	444
	M31183.1	-	3	409

More Information

Panther Classification:

Molecular Function -

major histocompatibility complex protein

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
adaptive immune response
antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
regulation of natural killer cell mediated immunity
positive regulation of natural killer cell mediated immunity
antibacterial humoral response
positive regulation of interleukin-13 production
positive regulation of interleukin-4 production
positive regulation of TRAIL production
positive regulation of tumor necrosis factor production
CD8-positive, alpha-beta T cell activation
protection from natural killer cell mediated cytotoxicity
innate immune response
regulation of immune response
defense response to Gram-positive bacterium
positive regulation of immunoglobulin secretion
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
positive regulation of CD8-positive, alpha-beta T cell proliferation

Function(s)

receptor binding
beta-2-microglobulin binding
MHC class I protein binding
peptide antigen binding
natural killer cell lectin-like receptor binding