21860

• Gene Symbol: EDEM1
• Gene Name: ER degradation enhancing alpha-mannosidase like protein 1
• Gene Aliases: EDEM
• Chromosome Location: Chr.3: 5187674 - 5219965 on Build GRCh38
• UniGene ID: Hs.224616
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EDEM1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_014674.2	NP_055489.1	5, 6	1173
	XM_011534271.2	XP_011532573.1	5, 6	1367
	XM_011534272.2	XP_011532574.1	6, 7	1166
GenBank mRNA	AK292643.1	-	5, 6	1041
	AK298511.1	-	5, 6	601
	AK302065.1	-	5, 6	642
	BC019088.1	-	5, 6	1180	4863779
	D86967.1	-	5, 6	1099

More Information

Gene Ontology Categories:

Process(es)

N-glycan processing
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
IRE1-mediated unfolded protein response
trimming of terminal mannose on C branch
glycoprotein ERAD pathway
positive regulation of retrograde protein transport, ER to cytosol
endoplasmic reticulum mannose trimming
mannose trimming involved in glycoprotein ERAD pathway

Function(s)

glycoprotein binding
alpha-mannosidase activity
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
calcium ion binding
protein binding
misfolded protein binding