220178

• Gene Symbol: Dnmt3a
• Gene Name: DNA (cytosine-5-)-methyltransferase 3 alpha
• Gene Aliases: -
• Chromosome Location: Chr.6: 28235695 - 28346052 on Build Rnor_6.0
• UniGene ID: Rn.92659
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dnmt3a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001003957.1	NP_001003957.1	6	854
	NM_001003958.1	NP_001003958.1	10	1536
	XM_008764530.1	XP_008762752.1	9	1395
	XM_008764531.1	XP_008762753.1	6	989

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001271753, NM_153743, NM_007872, BC007466, AK147263, and others.

Panther Classification:

Molecular Function -

DNA methyltransferase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
mitotic cell cycle
DNA methylation
methylation-dependent chromatin silencing
regulation of gene expression by genetic imprinting
transcription, DNA-templated
spermatogenesis
aging
response to toxic substance
response to ionizing radiation
response to lead ion
DNA methylation on cytosine within a CG sequence
positive regulation of cell death
neuron differentiation
response to nutrient levels
response to estradiol
DNA methylation on cytosine
response to vitamin A
response to antidepressant
response to cocaine
response to drug
DNA methylation involved in embryo development
DNA methylation involved in gamete generation
hypermethylation of CpG island
response to ethanol
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
cellular response to amino acid stimulus
cellular response to ethanol
cellular response to hypoxia
C-5 methylation of cytosine
hepatocyte apoptotic process

Function(s)

DNA binding
chromatin binding
DNA (cytosine-5-)-methyltransferase activity
identical protein binding
unmethylated CpG binding
metal ion binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates