22637

• Gene Symbol: PLCB1
• Gene Name: phospholipase C beta 1
• Gene Aliases: EIEE12, PI-PLC, PLC-154, PLC-I, PLC-beta-1, PLC154, PLCB1A, PLCB1B
• Chromosome Location: Chr.20: 8132236 - 8884911 on Build GRCh38
• UniGene ID: Hs.431173
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PLCB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_015192.3	NP_056007.1	1	467
	NM_182734.2	NP_877398.1	1	467
	XM_011529199.2	XP_011527501.1	1	427
	XM_017027752.1	XP_016883241.1	1	427
GenBank mRNA	AB011153.3	-	1	467
	AJ278313.1	-	1	83
	AJ278314.1	-	1	83
	AK310597.1	-	2	395
	BC069420.1	-	1	83	7262405
	BC117231.1	-	1	138	40125782

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001077641, XM_008762247, L14323, M20636.
This siRNA also targets the following transcripts in Mouse: NM_001145830, NM_019677, AF498250, AK141164, AK143153, and others.

Panther Classification:

Molecular Function -

phospholipase

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
signal transduction
G-protein coupled acetylcholine receptor signaling pathway
glutamate receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
memory
regulation of G-protein coupled receptor protein signaling pathway
lipid catabolic process
cerebral cortex development
positive regulation of interleukin-12 production
intracellular signal transduction
interleukin-12-mediated signaling pathway
interleukin-15-mediated signaling pathway
positive regulation of embryonic development
positive regulation of GTPase activity
inositol phosphate metabolic process
fat cell differentiation
positive regulation of myoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of JNK cascade
phosphatidylinositol metabolic process
insulin-like growth factor receptor signaling pathway
positive regulation of developmental growth
activation of meiosis involved in egg activation
interleukin-1-mediated signaling pathway
regulation of fertilization
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of acrosome reaction
negative regulation of monocyte extravasation
positive regulation of CD24 biosynthetic process

Function(s)

phosphatidylinositol phospholipase C activity
signal transducer activity
GTPase activator activity
calcium ion binding
protein binding
calmodulin binding
lamin binding
phosphatidylinositol-4,5-bisphosphate binding
enzyme binding
protein homodimerization activity