2266

• Gene Symbol: ALOX5
• Gene Name: arachidonate 5-lipoxygenase
• Gene Aliases: 5-LO, 5-LOX, 5LPG, LOG5
• Chromosome Location: Chr.10: 45374166 - 45446121 on Build GRCh38
• UniGene ID: Hs.89499
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ALOX5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000698.4	NP_000689.1	4	645
	NM_001256153.2	NP_001243082.1	4	645
	NM_001256154.2	NP_001243083.1	4	645
	NM_001320861.1	NP_001307790.1	4	645
	NM_001320862.1	NP_001307791.1	4	683
	XM_017016012.1	XP_016871501.1	3	520
GenBank mRNA	AB208946.1	-	5	2916
	AK225603.1	-	4	598
	AK315223.1	-	4	595
	BC034464.1	-	4	584
	BC040450.1	-	4	574
	BC130332.1	-	4	598	40146363
	BC132677.1	-	4	598	40146699
	BC143985.1	-	4	598	9052503
	HM592258.1	-	4	531
	HM592259.1	-	4	531
	HM592260.1	-	4	531
	HM592261.1	-	4	531
	J03571.1	-	4	565
	J03600.1	-	4	575
	JQ728550.1	-	3	451

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009662, AK137481, AK170879, BC139102, AK136868, and others.

Panther Classification:

Molecular Function -

oxygenase, reverse transcriptase

Gene Ontology Categories:

Process(es)

acute inflammatory response
leukotriene production involved in inflammatory response
leukotriene metabolic process
response to nutrient
sensory perception of pain
arachidonic acid metabolic process
leukotriene biosynthetic process
lipoxygenase pathway
positive regulation of vasoconstriction
response to hyperoxia
oxidation-reduction process
lipoxin metabolic process

Function(s)

arachidonate 5-lipoxygenase activity
iron ion binding
protein binding