22678

• Gene Symbol: ARHGEF4
• Gene Name: Rho guanine nucleotide exchange factor 4
• Gene Aliases: ASEF, ASEF1, GEF4, STM6
• Chromosome Location: Chr.2: 130836916 - 131047253 on Build GRCh38
• UniGene ID: Hs.469935
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ARHGEF4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_015320.3	NP_056135.2	5	1010
	NM_032995.2	NP_127462.1	4	599
	XM_005263681.1	XP_005263738.1	5	4087
	XM_005263687.3	XP_005263744.1	2	301
	XM_011511274.2	XP_011509576.1	5	4087
	XM_017004231.1	XP_016859720.1	5	4087
GenBank mRNA	AB029035.1	-	4	565
	AB042199.1	-	2	290
	AF249745.1	-	5	1011
	DQ424905.1	-	3	491

More Information

Panther Classification:

Molecular Function -

G-protein modulator, protein-binding activity modulator, guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

lamellipodium assembly
regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
filopodium assembly
regulation of small GTPase mediated signal transduction

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
protein domain specific binding
Rac guanyl-nucleotide exchange factor activity