22781

• Gene Symbol: ASXL1
• Gene Name: additional sex combs like 1, transcriptional regulator
• Gene Aliases: BOPS, MDS
• Chromosome Location: Chr.20: 32358062 - 32439319 on Build GRCh38
• UniGene ID: Hs.374043
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ASXL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001164603.1	NP_001158075.1	2	557
	NM_015338.5	NP_056153.2	2	557
	XM_006723727.3	XP_006723790.1	2	839
	XM_006723728.3	XP_006723791.1	2	166
	XM_006723730.3	XP_006723793.1	2	362
	XM_006723732.2	XP_006723795.1	2	338
	XM_011528648.2	XP_011526950.1	3	484
	XM_011528652.2	XP_011526954.1	3	1499
	XM_017027704.1	XP_016883193.1	2	1622
	XM_017027705.1	XP_016883194.1	2	635
	XM_017027706.1	XP_016883195.1	2	839
GenBank mRNA	AB084280.1	-	2	113
	AJ438952.2	-	2	383
	AK122923.1	-	2	338
	BC064984.1	-	2	542
	BC100280.1	-	2	551
	BC137278.1	-	3	320	9021275
	BC137280.1	-	3	320	9021277
	BQ064719.1	-		549

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008762396.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
heart morphogenesis
transcription, DNA-templated
response to retinoic acid
negative regulation of peroxisome proliferator activated receptor signaling pathway
monoubiquitinated histone H2A deubiquitination
negative regulation of fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of retinoic acid receptor signaling pathway
negative regulation of retinoic acid receptor signaling pathway
bone development
lung saccule development

Function(s)

DNA binding
transcription coactivator activity
transcription corepressor activity
protein binding
retinoic acid receptor binding
peroxisome proliferator activated receptor binding
metal ion binding