22931

• Gene Symbol: POT1
• Gene Name: protection of telomeres 1
• Gene Aliases: CMM10, GLM9, HPOT1
• Chromosome Location: Chr.7: 124822386 - 124929983 on Build GRCh38
• UniGene ID: Hs.31968
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: POT1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_015450.2	NP_056265.2	6, 7	727
	NR_003102.1		6, 7	727
	NR_003103.1		6, 7	727
	NR_003104.1		6, 7	727
	XM_006715917.3	XP_006715980.1	6, 7	717
	XM_011516006.1	XP_011514308.1	7, 8	839
	XM_011516007.1	XP_011514309.1	7, 8	838
	XM_017011941.1	XP_016867430.1	6, 7	725
GenBank mRNA	AK001230.1	-	2, 3	149
	AK001935.1	-	3, 4	256
	AK022580.1	-	6, 7	564
	AK302263.1	-	6, 7	882
	AY823520.1	-	2, 3	137
	AY823521.1	-	2, 3	137
	AY823522.1	-	2, 3	137
	AY823524.1	-	2, 3	137
	BC002923.2	-	3, 4	183	3955573

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001024322, XM_006236160, XM_006236161, XM_008762809, XM_008762810, and others.
This siRNA also targets the following transcripts in Mouse: NM_133931, AK085041, AK036052, BC016121, AK040864, and others.

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

telomere maintenance via telomerase
telomere capping
telomere assembly
positive regulation of telomere maintenance via telomerase
DNA duplex unwinding
positive regulation of helicase activity
positive regulation of telomerase activity
negative regulation of telomerase activity
positive regulation of DNA strand elongation
establishment of protein localization to telomere

Function(s)

protein binding
telomerase inhibitor activity
DEAD/H-box RNA helicase binding
telomeric DNA binding
single-stranded telomeric DNA binding
G-rich strand telomeric DNA binding