2305

• Gene Symbol: ALOX12B
• Gene Name: arachidonate 12-lipoxygenase, 12R type
• Gene Aliases: 12R-LOX, ARCI2
• Chromosome Location: Chr.17: 8072636 - 8087703 on Build GRCh38
• UniGene ID: Hs.136574
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ALOX12B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001139.2	NP_001130.1	1	360
GenBank mRNA	AF038461.1	-	1	358
	AF059250.1	-	1	136
	BC041058.1	-	1	388	5441563

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001039377, AY903232, AY903233, AY903231.
This siRNA also targets the following transcripts in Mouse: NM_009659, AF059251, Y14334, BC113149.

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

protein lipidation
sphingolipid metabolic process
positive regulation of gene expression
arachidonic acid metabolic process
lipoxygenase pathway
positive regulation of MAPK cascade
linoleic acid metabolic process
ceramide biosynthetic process
hepoxilin biosynthetic process
oxidation-reduction process
establishment of skin barrier
positive regulation of mucus secretion

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
protein binding
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
linoleate 9S-lipoxygenase activity