2306

• Gene Symbol: ALOX15
• Gene Name: arachidonate 15-lipoxygenase
• Gene Aliases: 12-LOX, 15-LOX-1, 15LOX-1
• Chromosome Location: Chr.17: 4630919 - 4641665 on Build GRCh38
• UniGene ID: Hs.73809
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ALOX15
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001140.3	NP_001131.3	1, 2	157
GenBank mRNA	AK290309.1	-	1, 2	170
	AK296792.1	-	1, 2	170
	AK296821.1	-	2, 3	242
	AK312557.1	-	1, 2	170
	BC029032.1	-	1, 2	157	5179700
	M23892.1	-	1, 2	146

More Information

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

ossification
negative regulation of adaptive immune response
phosphatidylethanolamine biosynthetic process
leukotriene metabolic process
inflammatory response
positive regulation of cell-substrate adhesion
arachidonic acid metabolic process
lipoxygenase pathway
bone mineralization
positive regulation of actin filament polymerization
positive regulation of heterotypic cell-cell adhesion
response to endoplasmic reticulum stress
regulation of peroxisome proliferator activated receptor signaling pathway
cellular response to interleukin-13
wound healing
apoptotic cell clearance
hepoxilin biosynthetic process
oxidation-reduction process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
regulation of engulfment of apoptotic cell
lipoxin A4 biosynthetic process

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
hepoxilin-epoxide hydrolase activity
arachidonate 15-lipoxygenase activity
hepoxilin A3 synthase activity
eoxin A4 synthase activity