23374

• Gene Symbol: UBR5
• Gene Name: ubiquitin protein ligase E3 component n-recognin 5
• Gene Aliases: DD5, EDD, EDD1, HYD
• Chromosome Location: Chr.8: 102252273 - 102412719 on Build GRCh38
• UniGene ID: Hs.492445
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: UBR5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001282873.1	NP_001269802.1	4	669
	NM_015902.5	NP_056986.2	4	669
	XM_011517104.2	XP_011515406.2	3	654
	XM_011517105.2	XP_011515407.2	3	654
	XM_011517106.2	XP_011515408.2	3	654
	XM_017013533.1	XP_016869022.1	3	654
	XM_017013534.1	XP_016869023.1	3	654
GenBank mRNA	AB020703.3	-	4	669
	AF006010.2	-	4	247
	BC137234.1	-	4	241	9021231
	U95000.1	-	4	214

More Information

Panther Classification:

Molecular Function -

ubiquitin-protein ligase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

protein polyubiquitination
DNA repair
ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
cell proliferation
positive regulation of protein import into nucleus, translocation
positive regulation of catenin import into nucleus
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
progesterone receptor signaling pathway
positive regulation of canonical Wnt signaling pathway
negative regulation of histone H2A K63-linked ubiquitination
negative regulation of double-strand break repair

Function(s)

RNA binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ubiquitin-ubiquitin ligase activity
ubiquitin binding