23547

• Gene Symbol: APH1A
• Gene Name: aph-1 homolog A, gamma-secretase subunit
• Gene Aliases: 6530402N02Rik, APH-1, APH-1A, CGI-78
• Chromosome Location: Chr.1: 150265399 - 150282291 on Build GRCh38
• UniGene ID: Hs.108408
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: APH1A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001243771.1	NP_001230700.1	5	974
	NM_016022.3	NP_057106.2	6	1145
	NR_045033.1		6	1009
	NR_045034.1		4	900
	NR_045035.1		5	1071
GenBank mRNA	AF151835.1	-	6	846
	AF508787.1	-	6	802
	AK027879.1	-	6	915
	AK075295.1	-	6	864
	AK075452.1	-	6	953
	AK125685.1	-	1	891
	AK297680.1	-	6	775
	AK298876.1	-	5	850
	AK300640.1	-	5	779
	AK307358.1	-	4	707
	AK314490.1	-	6	915
	AX775955.1	-	6	881
	AY113698.1	-	6	803
	AY358951.1	-	6	949
	BC008732.2	-	6	902	3162330
	BC009501.2	-	6	936	4040230
	BC017699.1	-	6	881	4177580

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001014255, BC087081.
This siRNA also targets the following transcripts in Mouse: NM_146104, BC057865, AK078343, AK152334, AK218564, and others.

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

metanephros development
membrane protein ectodomain proteolysis
Notch signaling pathway
Notch receptor processing
protein processing
membrane protein intracellular domain proteolysis
amyloid precursor protein catabolic process
positive regulation of apoptotic process
positive regulation of catalytic activity
ephrin receptor signaling pathway

Function(s)

endopeptidase activity
protein binding