2393

• Gene Symbol: SLC6A4
• Gene Name: solute carrier family 6 member 4
• Gene Aliases: 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
• Chromosome Location: Chr.17: 30194319 - 30235968 on Build GRCh38
• UniGene ID: Hs.134662
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SLC6A4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001045.5	NP_001036.1		839
GenBank mRNA	AK308014.1	-	3	570
	AK313166.1	-	3	568
	AU138385.1	-	3	568
	AY902473.1	-	1	334
	BC069484.1	-	1	311	7262380
	BX399758.2	-	3	598
	L05568.1	-	1	335
	X70697.1	-	1	373

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001045.

Panther Classification:

Molecular Function -

primary active transporter

Gene Ontology Categories:

Process(es)

response to hypoxia
serotonin transport
chemical synaptic transmission
response to nutrient
memory
circadian rhythm
response to toxic substance
positive regulation of gene expression
monoamine transport
thalamus development
negative regulation of cerebellar granule cell precursor proliferation
negative regulation of synaptic transmission, dopaminergic
response to estradiol
social behavior
vasoconstriction
response to drug
sperm ejaculation
negative regulation of neuron differentiation
positive regulation of cell cycle
negative regulation of organ growth
brain morphogenesis
protein oligomerization
protein homooligomerization
serotonin uptake
transmembrane transport
cellular response to retinoic acid
cellular response to cGMP

Function(s)

serotonin:sodium symporter activity
protein binding
monoamine transmembrane transporter activity
serotonin transmembrane transporter activity
myosin binding
syntaxin-1 binding
Rab GTPase binding
cocaine binding
protein homodimerization activity
metal ion binding
nitric-oxide synthase binding
actin filament binding