240520

• Gene Symbol: Atf3
• Gene Name: activating transcription factor 3
• Gene Aliases: LRG-21
• Chromosome Location: Chr.1: 191170296 - 191183333 on Build GRCm38
• UniGene ID: Mm.2706
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Atf3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007498.3	NP_031524.2	4	673
GenBank mRNA	AB291912.1	-		602
	AK133965.1	-	4	677
	AK156786.1	-	4	593
	AY329367.1	-	4	342
	BC019946.1	-	4	684	4011514
	BC064799.1	-	4	539	30054998
	CT010291.1	-	3	428
	D50524.1	-	3	428
	U19118.1	-	4	595

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001206486, NM_001040619, NM_001674, NM_001206484, NM_001030287, and others.

Panther Classification:

Molecular Function -

basic leucine zipper transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
gluconeogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
positive regulation of gene expression
endoplasmic reticulum unfolded protein response
cellular response to amino acid starvation
skeletal muscle cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of TRAIL-activated apoptotic signaling pathway
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
identical protein binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity