240533

• Gene Symbol: Stat1
• Gene Name: signal transducer and activator of transcription 1
• Gene Aliases: 2010005J02Rik, AA408197
• Chromosome Location: Chr.1: 52119438 - 52161865 on Build GRCm38
• UniGene ID: Mm.277406
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Stat1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001205313.1	NP_001192242.1	22	2221
	NM_001205314.1	NP_001192243.1	22	2239
	NM_009283.4	NP_033309.3	22	2254
GenBank mRNA	AK018544.1	-	22	2205
	AK039458.1	-	22	2255
	AK046517.1	-	22	2221
	AK082706.1	-	22	2236
	AK084855.1	-	22	2188
	AK157263.1	-	22	2103
	AK159887.1	-	22	2238
	BC042551.1	-	5	386
	U06924.1	-	19	1908

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: FQ231334.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of endothelial cell proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
JAK-STAT cascade
response to nutrient
blood circulation
positive regulation of cell proliferation
response to mechanical stimulus
response to bacterium
negative regulation of angiogenesis
cytokine-mediated signaling pathway
lipopolysaccharide-mediated signaling pathway
response to lipopolysaccharide
cellular response to insulin stimulus
tumor necrosis factor-mediated signaling pathway
response to cytokine
negative regulation of macrophage fusion
cellular response to interferon-beta
response to drug
negative regulation of I-kappaB kinase/NF-kappaB signaling
response to exogenous dsRNA
response to peptide hormone
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation by virus of viral protein levels in host cell
positive regulation of smooth muscle cell proliferation
response to cAMP
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
renal tubule development
cellular response to lipopolysaccharide

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
signal transducer activity
tumor necrosis factor receptor binding
protein binding
enzyme binding
CCR5 chemokine receptor binding
identical protein binding
protein homodimerization activity
sequence-specific DNA binding
protein phosphatase 2A binding