2417

• Gene Symbol: GCLM
• Gene Name: glutamate-cysteine ligase modifier subunit
• Gene Aliases: GLCLR
• Chromosome Location: Chr.1: 93885199 - 93909598 on Build GRCh38
• UniGene ID: Hs.315562
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GCLM
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002061.3	NP_002052.1	2, 3	634
	XM_011541261.2	XP_011539563.1	2, 3	435
	XM_017001056.1	XP_016856545.1	2, 3	634
GenBank mRNA	AK290449.1	-	2, 3	633
	BC041809.1	-	2, 3	435	5311598
	BU600458.1	-		495
	CR541833.1	-	2, 3	199
	L35546.1	-	2, 3	452

More Information

Panther Classification:

Molecular Function -

ligase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

sulfur amino acid metabolic process
cysteine metabolic process
glutamate metabolic process
glutathione biosynthetic process
response to oxidative stress
apoptotic mitochondrial changes
positive regulation of glutamate-cysteine ligase activity
response to drug
negative regulation of neuron apoptotic process
regulation of blood vessel size
response to nitrosative stress
regulation of mitochondrial depolarization
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

glutamate-cysteine ligase activity
enzyme regulator activity
glutamate-cysteine ligase catalytic subunit binding
protein heterodimerization activity