241764

• Gene Symbol: MAVS
• Gene Name: mitochondrial antiviral signaling protein
• Gene Aliases: CARDIF, IPS-1, IPS1, VISA
• Chromosome Location: Chr.20: 3846799 - 3876123 on Build GRCh38
• UniGene ID: Hs.570362
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MAVS
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001206491.1	NP_001193420.1	6	2379
	NM_020746.4	NP_065797.2	7	2554
	NR_037921.1		6	2381
GenBank mRNA	AB033097.1	-	6	2460
	AB097003.1	-	8	1918
	AB232371.1	-	6	2454
	AK023799.1	-	7	2509
	AK123956.1	-	4	376
	AL833736.1	-	1	2609
	BC044952.1	-	7	2488	5751684
	BX649084.1	-	6	2340

More Information

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
activation of innate immune response
positive regulation of defense response to virus by host
signal transduction
negative regulation of type I interferon production
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of protein import into nucleus, translocation
RIG-I signaling pathway
defense response to bacterium
positive regulation of transcription factor import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of viral genome replication
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of sequence-specific DNA binding transcription factor activity
defense response to virus
positive regulation of type I interferon-mediated signaling pathway
cellular response to exogenous dsRNA
positive regulation of chemokine (C-C motif) ligand 5 production
positive regulation of IP-10 production
regulation of peroxisome organization

Function(s)

signal transducer activity
protein binding
protein kinase binding
CARD domain binding