242311

• Gene Symbol: RIPK3
• Gene Name: receptor interacting serine/threonine kinase 3
• Gene Aliases: RIP3
• Chromosome Location: Chr.14: 24336021 - 24340036 on Build GRCh38
• UniGene ID: Hs.268551
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RIPK3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006871.3	NP_006862.2	10	1777
GenBank mRNA	AK075275.1	-	10	1732
	BC062584.1	-	10	1708	5213027

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

regulation of T cell mediated cytotoxicity
regulation of adaptive immune response
cellular protein modification process
signal transduction
I-kappaB kinase/NF-kappaB signaling
positive regulation of phosphatase activity
activation of protein kinase activity
regulation of interferon-gamma production
T cell differentiation in thymus
NIK/NF-kappaB signaling
T cell homeostasis
regulation of activated T cell proliferation
protein autophosphorylation
lymph node development
spleen development
thymus development
positive regulation of NF-kappaB transcription factor activity
protein homooligomerization
protein heterooligomerization
positive regulation of ligase activity
positive regulation of oxidoreductase activity
positive regulation of necroptotic process
regulation of activation-induced cell death of T cells
necroptotic process
positive regulation of protein deacetylation
apoptotic signaling pathway
amyloid fibril formation
positive regulation of reactive oxygen species metabolic process
regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

transcription coactivator activity
protein kinase activity
protein serine/threonine kinase activity
NF-kappaB-inducing kinase activity
protein binding
ATP binding
protein complex binding
identical protein binding