242379

• Gene Symbol: CDKN1B
• Gene Name: cyclin dependent kinase inhibitor 1B
• Gene Aliases: CDKN4, KIP1, MEN1B, MEN4, P27KIP1
• Chromosome Location: Chr.12: 12717270 - 12722383 on Build GRCh38
• UniGene ID: Hs.238990
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CDKN1B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004064.4	NP_004055.1	3	2327
GenBank mRNA	AA833962.1	-	1	351
	AY004255.1	-	3	1909
	BC001971.1	-	3	2134	3458141

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_006237539, AY623023, AY623024.
This siRNA also targets the following transcripts in Mouse: NM_009875, AK169586, AK154276.

Panther Classification:

Molecular Function -

kinase inhibitor

Gene Ontology Categories:

Process(es)

regulation of cyclin-dependent protein serine/threonine kinase activity
G1/S transition of mitotic cell cycle
response to hypoxia
potassium ion transport
activation of cysteine-type endopeptidase activity involved in apoptotic process
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
cell cycle arrest
Notch signaling pathway
sensory perception of sound
positive regulation of cell proliferation
negative regulation of cell proliferation
response to glucose
positive regulation of cell death
negative regulation of cell growth
positive regulation of microtubule polymerization
response to estradiol
negative regulation of kinase activity
negative regulation of phosphorylation
response to drug
negative regulation of apoptotic process
response to amino acid
response to peptide hormone
positive regulation of protein catabolic process
negative regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
negative regulation of mitotic cell cycle
response to cadmium ion
autophagic cell death
inner ear development
negative regulation of cellular component movement
negative regulation of epithelial cell proliferation involved in prostate gland development
cellular response to antibiotic
cellular response to lithium ion
cellular response to organic cyclic compound
mitotic cell cycle arrest
negative regulation of vascular smooth muscle cell proliferation

Function(s)

cyclin-dependent protein serine/threonine kinase inhibitor activity
transforming growth factor beta receptor, cytoplasmic mediator activity
protein binding
cysteine-type endopeptidase activator activity involved in apoptotic process
protein phosphatase binding
Hsp70 protein binding
protein complex binding
chaperone binding