242559

• Gene Symbol: MYD88
• Gene Name: myeloid differentiation primary response 88
• Gene Aliases: MYD88D
• Chromosome Location: Chr.3: 38138478 - 38143022 on Build GRCh38
• UniGene ID: Hs.82116
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MYD88
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001172566.1	NP_001166037.1	3	2139
	NM_001172567.1	NP_001166038.1	5	2479
	NM_001172568.1	NP_001166039.1	4	2320
	NM_001172569.1	NP_001166040.1	4	2274
	NM_002468.4	NP_002459.2	5	2455
	XM_005265172.1	XP_005265229.1	5	2431
	XM_006713170.1	XP_006713233.1	4	2122
GenBank mRNA	AK097983.1	-	1	2178
	AK124685.1	-	2	2922
	AL832906.1	-	5	2292
	BC013589.1	-	5	2271	3900951
	BX537602.1	-	3	2336
	U70451.1	-	5	2264

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

toll-like receptor signaling pathway
MyD88-dependent toll-like receptor signaling pathway
apoptotic process
inflammatory response
signal transduction
cell surface receptor signaling pathway
positive regulation of type I interferon production
positive regulation of interleukin-17 production
positive regulation of interleukin-23 production
positive regulation of interleukin-6 production
toll-like receptor 9 signaling pathway
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
regulation of inflammatory response
defense response to Gram-positive bacterium
positive regulation of NF-kappaB transcription factor activity
response to interleukin-1
3'-UTR-mediated mRNA stabilization
cellular response to mechanical stimulus

Function(s)

death receptor binding
protein binding
identical protein binding
protein self-association
TIR domain binding