24675

• Gene Symbol: POLA1
• Gene Name: DNA polymerase alpha 1, catalytic subunit
• Gene Aliases: NSX, POLA, p180
• Chromosome Location: Chr.X: 24693833 - 24996986 on Build GRCh38
• UniGene ID: Hs.567319
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: POLA1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_016937.3	NP_058633.2	2	143
	XM_005274552.3	XP_005274609.1	2	275
	XM_006724499.2	XP_006724562.1	2	182
	XM_011545540.2	XP_011543842.1	2	230
	XM_011545541.2	XP_011543843.1	2	231
	XM_017029594.1	XP_016885083.1	2	231
	XM_017029595.1	XP_016885084.1	2	231
	XM_017029596.1	XP_016885085.1	2	231
GenBank mRNA	BX648513.1	-	2	168
	DW462890.1	-	2	186
	X06745.1	-	2	144

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053479, AJ011605.

Panther Classification:

Molecular Function -

DNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
telomere maintenance via recombination
DNA synthesis involved in DNA repair
DNA replication
DNA replication, synthesis of RNA primer
DNA replication initiation
DNA strand elongation involved in DNA replication
leading strand elongation
lagging strand elongation
DNA repair
double-strand break repair via nonhomologous end joining
cell proliferation
viral process
nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleotide binding
nucleoside binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
DNA primase activity
protein binding
3'-5' exonuclease activity
protein kinase binding
metal ion binding
protein heterodimerization activity
4 iron, 4 sulfur cluster binding