2487

• Gene Symbol: ALOX15B
• Gene Name: arachidonate 15-lipoxygenase, type B
• Gene Aliases: 15-LOX-2
• Chromosome Location: Chr.17: 8039040 - 8049134 on Build GRCh38
• UniGene ID: Hs.111256
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ALOX15B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001039130.1	NP_001034219.1	13	2143
	NM_001039131.1	NP_001034220.1	12	2008
	NM_001141.2	NP_001132.2	14	2230
GenBank mRNA	AK292779.1	-	14	2226
	AK298095.1	-	14	2200
	BC035217.1	-	14	2172	4778890
	BC063647.1	-	14	2186	4804186
	U78294.1	-	14	2185

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: AF415240.

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

lipid metabolic process
apoptotic process
negative regulation of cell proliferation
positive regulation of macrophage derived foam cell differentiation
arachidonic acid metabolic process
lipoxygenase pathway
negative regulation of cell migration
prostate gland development
regulation of epithelial cell differentiation
positive regulation of peroxisome proliferator activated receptor signaling pathway
linoleic acid metabolic process
positive regulation of keratinocyte differentiation
negative regulation of cell cycle
negative regulation of growth
hepoxilin biosynthetic process
oxidation-reduction process
positive regulation of chemokine secretion

Function(s)

iron ion binding
calcium ion binding
lipid binding
linoleate 13S-lipoxygenase activity
arachidonate 8(S)-lipoxygenase activity
arachidonate 15-lipoxygenase activity