24921

• Gene Symbol: SMG6
• Gene Name: SMG6, nonsense mediated mRNA decay factor
• Gene Aliases: C17orf31, EST1A, SMG-6, hSMG5/7a
• Chromosome Location: Chr.17: 2059839 - 2303836 on Build GRCh38
• UniGene ID: Hs.448342
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SMG6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001256827.1	NP_001243756.1	7	959
	NM_001256828.1	NP_001243757.1	6	716
	NM_001282326.1	NP_001269255.1	2	1718
	NM_017575.4	NP_060045.4	14	3443
	XM_005256569.3	XP_005256626.1	14	3641
	XM_005256571.4	XP_005256628.1	6	2026
	XM_011523769.2	XP_011522071.1	15	3631
	XM_011523775.2	XP_011522077.1	7	2035
	XM_017024399.1	XP_016879888.1	14	2501
GenBank mRNA	AB018275.2	-	14	3480
	AK074270.1	-	6	705
	AK302964.1	-	6	716
	AL133597.1	-	2	1718
	AY145883.1	-	14	3393
	AY168921.1	-	13	3295
	BC064916.1	-	7	959

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001105808, XM_008767960, AY383695.
This siRNA also targets the following transcripts in Mouse: NM_001002764, BC077715, AK129203, BC037179, BC066040, and others.

Panther Classification:

Molecular Function -

RNA metabolism protein

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
telomere maintenance
mRNA export from nucleus
regulation of telomere maintenance via telomerase
regulation of dephosphorylation
RNA phosphodiester bond hydrolysis, endonucleolytic
negative regulation of telomere capping

Function(s)

endoribonuclease activity
protein binding
telomeric DNA binding
ribonucleoprotein complex binding
metal ion binding
telomerase RNA binding
DNA polymerase binding