251298

• Gene Symbol: PTPRC
• Gene Name: protein tyrosine phosphatase, receptor type C
• Gene Aliases: B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
• Chromosome Location: Chr.1: 198638968 - 198757476 on Build GRCh38
• UniGene ID: Hs.654514
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PTPRC
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001267798.1	NP_001254727.1	2	188
	NM_002838.4	NP_002829.3	2	188
	NM_080921.3	NP_563578.2	2	188
	NR_052021.1		2	188
	XM_006711472.3	XP_006711535.1	2	149
	XM_006711473.3	XP_006711536.1	2	131
	XM_006711474.3	XP_006711537.1	2	131
GenBank mRNA	AK130573.1	-	2	61
	AK292131.1	-	2	61
	AK299986.1	-	2	61
	AK303539.1	-	2	61
	AK307635.1	-	2	66
	AK308217.1	-	2	137
	AK310898.1	-	2	84
	BC014239.2	-	2	52
	BC017863.1	-	2	60
	DA670254.1	-	2	91
	DA819314.1	-	2	188
	Y00062.1	-	3	115
	Y00638.1	-	2	55

More Information

Panther Classification:

Molecular Function -

protein phosphatase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of T cell mediated cytotoxicity
negative regulation of cytokine-mediated signaling pathway
hematopoietic progenitor cell differentiation
immunoglobulin biosynthetic process
negative regulation of protein kinase activity
protein dephosphorylation
negative regulation of cell adhesion involved in substrate-bound cell migration
cell surface receptor signaling pathway
dephosphorylation
T cell differentiation
positive regulation of B cell proliferation
peptidyl-tyrosine dephosphorylation
B cell proliferation
positive regulation of T cell proliferation
cell cycle phase transition
positive regulation of protein kinase activity
bone marrow development
stem cell development
T cell receptor signaling pathway
B cell receptor signaling pathway
positive regulation of antigen receptor-mediated signaling pathway
release of sequestered calcium ion into cytosol
defense response to virus
regulation of cell cycle
positive regulation of hematopoietic stem cell migration
positive regulation of stem cell proliferation

Function(s)

protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
protein binding
protein kinase binding