251309

• Gene Symbol: PDPK1
• Gene Name: 3-phosphoinositide dependent protein kinase 1
• Gene Aliases: PDK1, PDPK2, PDPK2P, PRO0461
• Chromosome Location: Chr.16: 2537964 - 2603190 on Build GRCh38
• UniGene ID: Hs.459691
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PDPK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001261816.1	NP_001248745.1	12	6797
	NM_002613.4	NP_002604.1	14	7008
	NM_031268.5	NP_112558.2	11	6627
	XM_011522521.2	XP_011520823.1	14	10696
	XM_011522523.2	XP_011520825.1	11	10320
	XM_017023271.1	XP_016878760.1	13	11076
	XM_017023272.1	XP_016878761.1	13	7632
	XM_017023273.1	XP_016878762.1	13	7341
	XM_017023274.1	XP_016878763.1	14	7479
	XM_017023275.1	XP_016878764.1	10	10701
	XM_017023276.1	XP_016878765.1	10	6945
	XM_017023277.1	XP_016878766.1	11	7043
GenBank mRNA	AK095507.1	-	1	2392
	BC000789.1	-	1	186
	BC012540.1	-	1	859

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001286662, NM_011062, AK079579.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

stimulatory C-type lectin receptor signaling pathway
type B pancreatic cell development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
epidermal growth factor receptor signaling pathway
positive regulation of phospholipase activity
regulation of endothelial cell migration
negative regulation of cardiac muscle cell apoptotic process
cell migration
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
calcium-mediated signaling
actin cytoskeleton organization
platelet activation
negative regulation of transforming growth factor beta receptor signaling pathway
T cell costimulation
activation of protein kinase B activity
cellular response to insulin stimulus
negative regulation of toll-like receptor signaling pathway
intracellular signal transduction
Fc-epsilon receptor signaling pathway
regulation of I-kappaB kinase/NF-kappaB signaling
regulation of mast cell degranulation
protein autophosphorylation
phosphatidylinositol-mediated signaling
focal adhesion assembly
T cell receptor signaling pathway
positive regulation of release of sequestered calcium ion into cytosol
cellular response to epidermal growth factor stimulus
positive regulation of establishment of protein localization to plasma membrane
extrinsic apoptotic signaling pathway

Function(s)

protein serine/threonine kinase activity
3-phosphoinositide-dependent protein kinase activity
insulin receptor binding
protein binding
ATP binding
phospholipase activator activity
kinase activity
protein kinase binding
phospholipase binding