2536

• Gene Symbol: TAP1
• Gene Name: transporter 1, ATP binding cassette subfamily B member
• Gene Aliases: ABC17, ABCB2, APT1, D6S114E, PSF-1, PSF1, RING4, TAP1*0102N, TAP1N
• Chromosome Location: Chr.6: 32845209 - 32853971 on Build GRCh38
• UniGene ID: Hs.352018
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TAP1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000593.5	NP_000584.2	3	1156
	NM_001292022.1	NP_001278951.1	3	416
GenBank mRNA	AB012644.1	-	3	820
	AK302340.1	-	3	387
	AK313762.1	-	3	1192
	AY523970.1	-	3	1027
	AY523971.2	-	3	1027
	BC014081.2	-	3	1156	4304716
	BX648013.1	-	3	1164
	DC354917.1	-	3	416
	KU178346.1	-	3	1001
	L21204.1	-	3	821
	L21205.1	-	3	821
	L21206.1	-	3	821
	L21207.1	-	3	821
	L21208.1	-	3	821
	X57521.1	-	3	455
	X57522.1	-	3	1031

More Information

Panther Classification:

Molecular Function -

ATP-binding cassette (ABC) transporter

Gene Ontology Categories:

Process(es)

adaptive immune response
antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
positive regulation of antigen processing and presentation of peptide antigen via MHC class I
defense response
peptide transport
intracellular transport of viral protein in host cell
antigen processing and presentation of endogenous peptide antigen via MHC class I
protection from natural killer cell mediated cytotoxicity
cytosol to ER transport
transmembrane transport

Function(s)

protein binding
ATP binding
peptide transporter activity
peptide-transporting ATPase activity
MHC class Ib protein binding
MHC class I protein binding
peptide antigen binding
ATPase activity, coupled to transmembrane movement of substances
protein homodimerization activity
ADP binding
TAP1 binding
TAP2 binding
tapasin binding
protein heterodimerization activity