253836

• Gene Symbol: Shc1
• Gene Name: SHC (Src homology 2 domain containing) transforming protein 1
• Gene Aliases: P66shc
• Chromosome Location: Chr.2: 188745503 - 188757066 on Build Rnor_6.0
• UniGene ID: Rn.138818
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Shc1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001164060.1	NP_001157532.1	1	666
	NM_053517.2	NP_445969.2	2	233
GenBank mRNA	BC088298.1	-	2	233	7323045
	D83015.1	-	1	14

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003029, NM_001130040, NM_001202859, NM_183001, NM_001130041, and others.
This siRNA also targets the following transcripts in Mouse: NM_011368, NM_001113331, AK155158, BC036172, AK036980, and others.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
angiogenesis
response to hypoxia
epidermal growth factor receptor signaling pathway
heart development
aging
insulin receptor signaling pathway
response to toxic substance
response to organic cyclic compound
single organismal cell-cell adhesion
actin cytoskeleton organization
neuron differentiation
organ regeneration
neuron projection development
actin cytoskeleton reorganization
response to insulin
cellular response to insulin stimulus
response to nicotine
intracellular signal transduction
regulation of growth
regulation of cell proliferation
response to hydrogen peroxide
positive regulation of DNA replication
positive regulation of vasoconstriction
positive regulation of smooth muscle cell proliferation
response to glucocorticoid

Function(s)

phosphotyrosine binding
epidermal growth factor receptor binding
insulin receptor binding
insulin-like growth factor receptor binding
neurotrophin TRKA receptor binding
protein binding
protein kinase binding
receptor tyrosine kinase binding
protein complex binding
ephrin receptor binding
phosphoprotein binding
protein phosphatase 2A binding