258994

• Gene Symbol: Ace
• Gene Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
• Gene Aliases: AW208573, CD143
• Chromosome Location: Chr.11: 105967945 - 105989964 on Build GRCm38
• UniGene ID: Mm.754
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ace
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001281819.1	NP_001268748.1	16, 17	2502
	NM_009598.2	NP_033728.1	5, 6	725
	NM_207624.5	NP_997507.1	16, 17	2502
GenBank mRNA	AK154632.1	-	16, 17	2501
	AK161020.1	-	16, 17	2498
	AK164780.1	-	3, 4	370
	BC034367.1	-	12, 13	1764
	BC040404.1	-	16, 17	2491	3965649
	BC083109.1	-	16, 17	2280
	BC110362.1	-	16, 17	2488	5343978
	J04946.1	-	10, 11	1469
	J04947.1	-		1469
	M55333.1	-	5, 6	725

More Information

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

kidney development
neutrophil mediated immunity
regulation of systemic arterial blood pressure by renin-angiotensin
positive regulation of systemic arterial blood pressure
proteolysis
peptide metabolic process
spermatogenesis
regulation of blood pressure
posttranscriptional regulation of gene expression
negative regulation of gene expression
bradykinin catabolic process
regulation of smooth muscle cell migration
sensory perception of pain
organ regeneration
negative regulation of protein binding
positive regulation of protein binding
response to lipopolysaccharide
vasoconstriction
hormone catabolic process
eating behavior
positive regulation of apoptotic process
peptide catabolic process
lung alveolus development
beta-amyloid metabolic process
arachidonic acid secretion
positive regulation of inflammatory response
positive regulation of neurogenesis
heart contraction
regulation of angiotensin metabolic process
angiogenesis involved in coronary vascular morphogenesis
positive regulation of protein tyrosine kinase activity
cell proliferation in bone marrow
negative regulation of calcium ion import
positive regulation of peptidyl-tyrosine autophosphorylation
regulation of hematopoietic stem cell proliferation
negative regulation of gap junction assembly
positive regulation of peptidyl-cysteine S-nitrosylation

Function(s)

actin binding
endopeptidase activity
carboxypeptidase activity
protein binding
drug binding
peptidase activity
metallopeptidase activity
exopeptidase activity
tripeptidyl-peptidase activity
peptidyl-dipeptidase activity
zinc ion binding
lytic transglycosylase activity
mannosidase activity
mannosyl-oligosaccharide mannosidase activity
galactosidase activity
glucosidase activity
trehalase activity
fucosidase activity
hexosaminidase activity
amylase activity
hydrolase activity
chloride ion binding
mitogen-activated protein kinase kinase binding
bradykinin receptor binding
dextrin alpha-glucosidase activity
starch alpha-glucosidase activity
metal ion binding
mitogen-activated protein kinase binding
beta-glucanase activity
beta-6-sulfate-N-acetylglucosaminidase activity
glucan endo-1,4-beta-glucosidase activity