259496

• Gene Symbol: Arhgef2
• Gene Name: rho/rac guanine nucleotide exchange factor (GEF) 2
• Gene Aliases: -
• Chromosome Location: Chr.2: 187964079 - 188022847 on Build Rnor_6.0
• UniGene ID: Rn.12255
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Arhgef2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001012079.1	NP_001012079.1	22	3221
	XM_006232643.2	XP_006232705.1	27	3999
	XM_006232644.2	XP_006232706.1	28	4116
	XM_006232646.2	XP_006232708.1	26	3576
	XM_006232647.2	XP_006232709.1	25	3420
	XM_006232648.2	XP_006232710.1	25	3371
	XM_006232651.2	XP_006232713.1	22	3509
	XM_006232652.2	XP_006232714.1	22	3328
	XM_006232653.2	XP_006232715.1	22	3216
	XM_006232654.2	XP_006232716.1	22	4025
	XM_008761151.1	XP_008759373.1	28	4111
	XM_008761152.1	XP_008759374.1	23	4099
GenBank mRNA	BC090078.1	-	22	3221	7125049
	FQ212011.1	-	23	3194

More Information

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
cell morphogenesis
actin filament organization
negative regulation of microtubule depolymerization
mitotic nuclear division
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of Rho protein signal transduction
intracellular signal transduction
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of neurogenesis
positive regulation of NF-kappaB transcription factor activity
cell division
cellular response to muramyl dipeptide

Function(s)

Rho guanyl-nucleotide exchange factor activity
microtubule binding
Rho GTPase binding
Rac guanyl-nucleotide exchange factor activity
metal ion binding
Rac GTPase binding