2614

• Gene Symbol: BRCA2
• Gene Name: BRCA2, DNA repair associated
• Gene Aliases: BRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, FANCD1, GLM3, PNCA2, XRCC11
• Chromosome Location: Chr.13: 32315480 - 32399672 on Build GRCh38
• UniGene ID: Hs.34012
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BRCA2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000059.3	NP_000050.2	6, 7	751
GenBank mRNA	BC026160.1	-	6, 7	727
	BC047568.1	-	6, 7	722
	DQ897648.1	-	5, 6	524
	U43746.1	-	6, 7	752

More Information

Panther Classification:

Molecular Function -

damaged DNA-binding protein

Gene Ontology Categories:

Process(es)

telomere maintenance via recombination
double-strand break repair via homologous recombination
DNA synthesis involved in DNA repair
strand displacement
cytokinesis
oocyte maturation
inner cell mass cell proliferation
nucleotide-excision repair
double-strand break repair
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
male meiosis I
spermatogenesis
brain development
cell aging
response to nutrient
female gonad development
response to X-ray
response to UV-C
response to gamma radiation
hemopoiesis
mammary gland development
chromosome breakage
homologous chromosome orientation involved in meiotic metaphase I plate congression
response to estradiol
regulation of cytokinesis
negative regulation of mammary gland epithelial cell proliferation
multicellular organism growth
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
histone H3 acetylation
histone H4 acetylation
positive regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
replication fork protection
centrosome duplication
establishment of protein localization to telomere
mitotic recombination-dependent replication fork processing

Function(s)

protease binding
single-stranded DNA binding
histone acetyltransferase activity
protein binding
H3 histone acetyltransferase activity
H4 histone acetyltransferase activity
gamma-tubulin binding