261617

• Gene Symbol: Ep300
• Gene Name: E1A binding protein p300
• Gene Aliases: A430090G16, A730011L11, KAT3B, p300, p300 HAT
• Chromosome Location: Chr.15: 81586214 - 81652077 on Build GRCm38
• UniGene ID: Mm.258397
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ep300
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_177821.6	NP_808489.4	5, 6	1695
GenBank mRNA	AK042627.1	-	5, 6	1691
	AK139715.1	-	2, 3	187
	BC144976.1	-	5, 6	1549	9053524
	BC150681.1	-	5, 6	1549	9087592

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008765878.

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
response to hypoxia
somitogenesis
positive regulation of protein phosphorylation
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein acetylation
internal protein amino acid acetylation
apoptotic process
positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
cell cycle
heart development
skeletal muscle tissue development
circadian rhythm
response to glucose
organ morphogenesis
positive regulation of glycoprotein biosynthetic process
positive regulation of gene expression
positive regulation of cell death
positive regulation of muscle atrophy
histone acetylation
N-terminal peptidyl-lysine acetylation
internal peptidyl-lysine acetylation
cell differentiation
positive regulation of cell growth
lung development
negative regulation of cellular metabolic process
positive regulation of cellular metabolic process
positive regulation of protein binding
positive regulation of collagen biosynthetic process
positive regulation of protein import into nucleus, translocation
cellular response to UV
positive regulation of histone acetylation
response to drug
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of DNA binding
protein kinase B signaling
response to estrogen
positive regulation by host of viral transcription
histone H3 acetylation
histone H4 acetylation
histone H2B acetylation
positive regulation of translation
positive regulation of axon extension
positive regulation of cell size
positive regulation of proteolysis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
positive regulation of protein secretion
protein stabilization
positive regulation of sequence-specific DNA binding transcription factor activity
cartilage development
response to calcium ion
regulation of angiotensin metabolic process
positive regulation of sarcomere organization
negative regulation of cell death
regulation of androgen receptor signaling pathway
protein-DNA complex assembly
response to dexamethasone
regulation of tubulin deacetylation
positive regulation of protein acetylation
regulation of nucleic acid-templated transcription
negative regulation of miRNA metabolic process

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
core promoter binding
RNA polymerase II transcription factor binding
RNA polymerase II activating transcription factor binding
core promoter proximal region DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
transcription factor activity, sequence-specific DNA binding
transcription cofactor activity
transcription coactivator activity
antigen binding
histone acetyltransferase activity
lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
protein binding
beta-catenin binding
protein C-terminus binding
transcription factor binding
zinc ion binding
acetyltransferase activity
transferase activity
transferase activity, transferring acyl groups
protein kinase binding
chromatin DNA binding
protein complex binding
activating transcription factor binding
nuclear hormone receptor binding
glucocorticoid receptor binding
peroxisome proliferator activated receptor binding
bHLH transcription factor binding
SMAD binding
metal ion binding
androgen receptor binding
mitogen-activated protein kinase binding
NF-kappaB binding
pre-mRNA intronic binding
protein antigen binding