26448

• Gene Symbol: EDEM2
• Gene Name: ER degradation enhancing alpha-mannosidase like protein 2
• Gene Aliases: C20orf31, C20orf49, bA4204.1
• Chromosome Location: Chr.20: 35115357 - 35147358 on Build GRCh38
• UniGene ID: Hs.720177
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EDEM2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001145025.1	NP_001138497.1	5	577
	NM_018217.2	NP_060687.2	6	688
	NR_026728.1		5	904
GenBank mRNA	AK001645.1	-	6	670
	AK023931.1	-	6	658
	AK096016.1	-	4	598
	AK293583.1	-	4	508
	AK298794.1	-	5	646
	AK300212.1	-	5	532
	AY007088.1	-	3	256
	AY358580.1	-	5	538
	BC001371.2	-	6	655	3051376
	BC016184.1	-	6	629	4860424
	CR457266.1	-	6	588

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001004230, BC079029.
This siRNA also targets the following transcripts in Mouse: NM_145537, AK149892, AK166998, AK187628, AK079296, and others.

Gene Ontology Categories:

Process(es)

N-glycan processing
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
trimming of terminal mannose on B branch
glycoprotein ERAD pathway
positive regulation of retrograde protein transport, ER to cytosol
endoplasmic reticulum mannose trimming
mannose trimming involved in glycoprotein ERAD pathway

Function(s)

glycoprotein binding
alpha-mannosidase activity
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
calcium ion binding