270 Validated

• Gene Symbol: PDPK1
• Gene Name: 3-phosphoinositide dependent protein kinase 1
• Gene Aliases: PDK1, PDPK2, PDPK2P, PRO0461
• Chromosome Location: Chr.16: 2537964 - 2603190 on Build GRCh38
• UniGene ID: Hs.459691
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PDPK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001261816.1	NP_001248745.1	2, 3	428
	NM_002613.4	NP_002604.1	2, 3	428
	NM_031268.5	NP_112558.2	2, 3	428
	XM_011522521.2	XP_011520823.1	2, 3	4116
	XM_011522523.2	XP_011520825.1	2, 3	4121
	XM_017023271.1	XP_016878760.1	2, 3	4121
	XM_017023272.1	XP_016878761.1	2, 3	677
	XM_017023273.1	XP_016878762.1	2, 3	386
	XM_017023274.1	XP_016878763.1	3, 4	524
	XM_017023275.1	XP_016878764.1	2, 3	4127
	XM_017023276.1	XP_016878765.1	2, 3	371
	XM_017023277.1	XP_016878766.1	2, 3	371
GenBank mRNA	AB209835.1	-	2, 3	395
	AF017995.1	-	2, 3	359
	AJ785968.1	-	1, 2	1062
	AK131060.1	-	2, 3	362
	AK222581.1	-	2, 3	371
	AK293900.1	-	2, 3	371
	BC006339.2	-	2, 3	389	4079551
	BC012103.1	-	2, 3	388	4561371
	BC033494.1	-	2, 3	341	5176294
	BI830733.1	-	2, 3	424
	CR536517.1	-	2, 3	279
	Y15056.1	-	2, 3	358

More Information

Matching Taqman Gene Expression Assay:

Hs00176884_m1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

stimulatory C-type lectin receptor signaling pathway
type B pancreatic cell development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
epidermal growth factor receptor signaling pathway
positive regulation of phospholipase activity
regulation of endothelial cell migration
negative regulation of cardiac muscle cell apoptotic process
cell migration
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
calcium-mediated signaling
actin cytoskeleton organization
platelet activation
negative regulation of transforming growth factor beta receptor signaling pathway
T cell costimulation
activation of protein kinase B activity
cellular response to insulin stimulus
negative regulation of toll-like receptor signaling pathway
intracellular signal transduction
Fc-epsilon receptor signaling pathway
regulation of I-kappaB kinase/NF-kappaB signaling
regulation of mast cell degranulation
protein autophosphorylation
phosphatidylinositol-mediated signaling
focal adhesion assembly
T cell receptor signaling pathway
positive regulation of release of sequestered calcium ion into cytosol
cellular response to epidermal growth factor stimulus
positive regulation of establishment of protein localization to plasma membrane
extrinsic apoptotic signaling pathway

Function(s)

protein serine/threonine kinase activity
3-phosphoinositide-dependent protein kinase activity
insulin receptor binding
protein binding
ATP binding
phospholipase activator activity
kinase activity
protein kinase binding
phospholipase binding