27564

• Gene Symbol: TREM2
• Gene Name: triggering receptor expressed on myeloid cells 2
• Gene Aliases: TREM-2, Trem2a, Trem2b, Trem2c
• Chromosome Location: Chr.6: 41158506 - 41163200 on Build GRCh38
• UniGene ID: Hs.435295
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TREM2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001271821.1	NP_001258750.1	4	613
	NM_018965.3	NP_061838.1	5	807
	XM_006715116.3	XP_006715179.1	4	470
GenBank mRNA	AB062787.1	-	4	613
	AF213457.1	-	5	797
	BC032362.1	-	5	764	5240587

More Information

Panther Classification:

Molecular Function -

immunoglobulin receptor superfamily

Gene Ontology Categories:

Process(es)

positive regulation of antigen processing and presentation of peptide antigen via MHC class II
phagocytosis, engulfment
humoral immune response
detection of lipopolysaccharide
detection of peptidoglycan
innate immune response
positive regulation of peptidyl-tyrosine phosphorylation
regulation of immune response
positive regulation of calcium-mediated signaling
positive regulation of ERK1 and ERK2 cascade
detection of lipoteichoic acid
cellular response to lipoteichoic acid
cellular response to peptidoglycan
dendritic cell differentiation
positive regulation of protein localization to plasma membrane
positive regulation of C-C chemokine receptor CCR7 signaling pathway
positive regulation of CD40 signaling pathway

Function(s)

lipopolysaccharide binding
receptor activity
peptidoglycan binding
lipoteichoic acid binding
scaffold protein binding