2776

• Gene Symbol: STAT1
• Gene Name: signal transducer and activator of transcription 1
• Gene Aliases: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91
• Chromosome Location: Chr.2: 190969036 - 191014250 on Build GRCh38
• UniGene ID: Hs.642990
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: STAT1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007315.3	NP_009330.1	13, 14	1522
	NM_139266.2	NP_644671.1	13, 14	1522
	XM_006712718.1	XP_006712781.1	12, 13	1315
	XM_017004783.1	XP_016860272.1	14, 15	1552
GenBank mRNA	AK096686.1	-	14, 15	1539
	AK225853.1	-	12, 13	1408
	AK292604.1	-	12, 13	1566
	AK315002.1	-	13, 14	1437
	BC002704.2	-	13, 14	1440	3627218
	BT007241.1	-	11, 12	1134
	CR749636.1	-	13, 14	1429
	GU211347.1	-	12, 13	1198
	GU211348.1	-	11, 12	1106
	M97935.1	-	12, 13	1330
	M97936.1	-	12, 13	1330

More Information

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
negative regulation of endothelial cell proliferation
positive regulation of mesenchymal cell proliferation
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
transcription, DNA-templated
apoptotic process
JAK-STAT cascade
blood circulation
macrophage derived foam cell differentiation
negative regulation of angiogenesis
tumor necrosis factor-mediated signaling pathway
response to cytokine
response to interferon-beta
cellular response to interferon-beta
regulation of apoptotic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
response to peptide hormone
endothelial cell migration
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation by virus of viral protein levels in host cell
positive regulation of smooth muscle cell proliferation
response to cAMP
defense response to virus
interferon-gamma-mediated signaling pathway
regulation of interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
regulation of type I interferon-mediated signaling pathway
renal tubule development
cellular response to organic cyclic compound
metanephric mesenchymal cell proliferation involved in metanephros development
metanephric mesenchymal cell differentiation
negative regulation of metanephric nephron tubule epithelial cell differentiation
cell-cell adhesion

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
signal transducer activity
tumor necrosis factor receptor binding
protein binding
enzyme binding
nuclear hormone receptor binding
identical protein binding
protein homodimerization activity
cadherin binding involved in cell-cell adhesion