279278

Gene Symbol:

CYP2D7 CYP2D6 LOC101929829

Gene Name:

cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)

cytochrome P450 family 2 subfamily D member 6

cytochrome P450 family 2 subfamily D member 6 pseudogene

Gene Aliases:

CYP2D, CYP2D7AP, CYP2D7P, CYP2D7P1, CYP2D@, P450C2D, P450DB1, RNA40057

CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1

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Chromosome Location:

Chr.22: 42140203 - 42144575 on Build GRCh38

Chromosome Location:

Chr.22: 42125531 - 42130881 on Build GRCh38

Chromosome Location:

-

UniGene ID:

Hs.333497

Hs.648256

Hs.648256

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: CYP2D7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_002570.3		9	1672
GenBank mRNA	AY220845.1	-	10	1734

Gene Symbol: CYP2D6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000106.5	NP_000097.3	9	1650
	NM_001025161.2	NP_001020332.2	8	1497
GenBank mRNA	AY663390.1	-	7	1183

Gene Symbol: LOC101929829
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_111920.1		9	1649
GenBank mRNA	X16865.1	-	7	1194

More Information

Panther Classification:

Molecular Function -

oxidoreductase, oxygenase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

xenobiotic metabolic process
exogenous drug catabolic process
oxidation-reduction process
steroid metabolic process
coumarin metabolic process
alkaloid metabolic process
alkaloid catabolic process
monoterpenoid metabolic process
drug metabolic process
arachidonic acid metabolic process
isoquinoline alkaloid metabolic process
drug catabolic process
heterocycle metabolic process
negative regulation of binding
oxidative demethylation
negative regulation of cellular organofluorine metabolic process

Function(s)

iron ion binding
heme binding
aromatase activity
monooxygenase activity
drug binding
arachidonic acid epoxygenase activity
steroid hydroxylase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
oxygen binding