280729

• Gene Symbol: Stub1
• Gene Name: STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
• Gene Aliases: Chip
• Chromosome Location: Chr.10: 15197754 - 15200035 on Build Rnor_6.0
• UniGene ID: Rn.6504
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Stub1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001025625.2	NP_001020796.2	3	549
GenBank mRNA	BC099240.1	-	3	496	7445727
	CB568781.1	-	3	550

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_019719, AK045776, AK004464, AK158595, AK002752, and others.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

protein polyubiquitination
ubiquitin-dependent protein catabolic process
misfolded or incompletely synthesized protein catabolic process
ubiquitin-dependent SMAD protein catabolic process
endoplasmic reticulum unfolded protein response
positive regulation of protein ubiquitination
regulation of glucocorticoid metabolic process
negative regulation of protein binding
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of ubiquitin-protein transferase activity
protein autoubiquitination
protein K63-linked ubiquitination
cellular response to misfolded protein
positive regulation of chaperone-mediated protein complex assembly

Function(s)

G-protein coupled receptor binding
ubiquitin-protein transferase activity
protein binding
ligase activity
enzyme binding
kinase binding
Hsp70 protein binding
TPR domain binding
ubiquitin protein ligase binding
ubiquitin-ubiquitin ligase activity
protein homodimerization activity
SMAD binding
misfolded protein binding
Hsp90 protein binding
ubiquitin protein ligase activity