280844

• Gene Symbol: Hdac1
• Gene Name: histone deacetylase 1
• Gene Aliases: -
• Chromosome Location: Chr.5: 147716664 - 147743723 on Build Rnor_6.0
• UniGene ID: Rn.1863
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hdac1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001025409.1	NP_001020580.1	1	46
GenBank mRNA	BC059156.1	-	1	63
	BC097943.1	-	1	46	7458532
	BC107476.1	-	1	43	7443793

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008228, BC092070, X98207, U80780, BC108371.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
response to amphetamine
protein deacetylation
endoderm development
circadian rhythm
positive regulation of cell proliferation
negative regulation of cell proliferation
epidermal cell differentiation
negative regulation of myotube differentiation
positive regulation of receptor biosynthetic process
histone deacetylation
hippocampus development
neuron differentiation
response to caffeine
response to lipopolysaccharide
positive regulation of interleukin-1 production
positive regulation of tumor necrosis factor production
circadian regulation of gene expression
cellular response to oxidative stress
odontogenesis of dentin-containing tooth
response to drug
positive regulation of tyrosine phosphorylation of Stat3 protein
embryonic digit morphogenesis
ATP-dependent chromatin remodeling
negative regulation of apoptotic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of neuron apoptotic process
negative regulation by host of viral transcription
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of insulin secretion
positive regulation of oligodendrocyte differentiation
response to hyperoxia
negative regulation of androgen receptor signaling pathway
hair follicle placode formation
eyelid development in camera-type eye
fungiform papilla formation
histone H3 deacetylation
histone H4 deacetylation
cellular response to tumor necrosis factor
negative regulation of canonical Wnt signaling pathway
positive regulation of chemokine (C-X-C motif) ligand 2 production
positive regulation of type B pancreatic cell apoptotic process
negative regulation of peptidyl-lysine acetylation
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
core promoter binding
RNA polymerase II repressing transcription factor binding
RNA polymerase II transcription corepressor activity
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
histone deacetylase activity
protein binding
transcription factor binding
deacetylase activity
enzyme binding
nucleosomal DNA binding
protein complex binding
protein deacetylase activity
activating transcription factor binding
Krueppel-associated box domain binding
histone deacetylase binding
transcription regulatory region DNA binding
protein N-terminus binding
repressing transcription factor binding