284041

• Gene Symbol: Srebf2
• Gene Name: sterol regulatory element binding factor 2
• Gene Aliases: AI608257, SREBP-2, SREBP2, SREBP2gc, bHLHd2, lop13, nuc
• Chromosome Location: Chr.15: 82147269 - 82205379 on Build GRCm38
• UniGene ID: Mm.38016
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Srebf2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_033218.1	NP_150087.1	2	286
GenBank mRNA	AF374267.1	-	2	139
	AK032847.1	-	2	310
	AK053802.1	-	2	305
	AK155857.1	-	2	354
	AK172219.1	-	2	291
	AK217643.1	-	2	203
	BC014730.1	-	2	276
	BC026556.1	-	2	278
	BC038284.1	-	2	277
	BC048071.1	-	2	291
	BC069989.1	-	2	295
	BQ965109.1	-	2	293

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
lipid metabolic process
steroid metabolic process
cholesterol metabolic process
cellular response to starvation
response to hormone
positive regulation of cholesterol storage
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
negative regulation of cholesterol efflux
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
regulation of cholesterol homeostasis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein C-terminus binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein dimerization activity
E-box binding