2864

• Gene Symbol: NKX3-1
• Gene Name: NK3 homeobox 1
• Gene Aliases: BAPX2, NKX3, NKX3.1, NKX3A
• Chromosome Location: Chr.8: 23678693 - 23682937 on Build GRCh38
• UniGene ID: Hs.55999
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NKX3-1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001256339.1	NP_001243268.1	3	205
	NM_006167.3	NP_006158.2	2	478
GenBank mRNA	AF247704.1	-	2	478
	AF249669.1	-	3	308
	AF249670.1	-	2	293
	AF249671.1	-	3	233
	AF249672.1	-	3	215
	BC074863.2	-	2	462	30915465
	BC074864.2	-	2	462	30915229
	U80669.1	-	2	459
	U91540.1	-	2	430

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001034144, BC100628.
This siRNA also targets the following transcripts in Mouse: NM_010921, BC132401, BC132427, U88542, AK137281, and others.

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

metanephros development
somitogenesis
positive regulation of protein phosphorylation
transcription, DNA-templated
regulation of transcription, DNA-templated
activation of cysteine-type endopeptidase activity involved in apoptotic process
multicellular organism development
salivary gland development
heart development
positive regulation of cell proliferation
negative regulation of cell proliferation
male gonad development
positive regulation of gene expression
negative regulation of gene expression
positive regulation of cell death
positive regulation of phosphatidylinositol 3-kinase signaling
androgen receptor signaling pathway
activation of protein kinase activity
response to testosterone
cellular response to drug
dorsal aorta development
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
protein kinase B signaling
negative regulation of insulin-like growth factor receptor signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of mitotic cell cycle
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
branching morphogenesis of an epithelial tube
negative regulation of epithelial cell proliferation
positive regulation of cell division
pharyngeal system development
branching involved in prostate gland morphogenesis
epithelial cell proliferation involved in salivary gland morphogenesis
negative regulation of epithelial cell proliferation involved in prostate gland development
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to steroid hormone stimulus
cellular response to hypoxia
mitotic cell cycle arrest
negative regulation of estrogen receptor binding
positive regulation of androgen secretion
positive regulation of response to DNA damage stimulus
positive regulation of apoptotic signaling pathway
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

transcription regulatory region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
core promoter binding
transcription factor activity, sequence-specific DNA binding
androgen receptor activity
protein binding
transcription factor binding
cysteine-type endopeptidase activator activity involved in apoptotic process
estrogen receptor activity
protein kinase activator activity
estrogen receptor binding
histone deacetylase binding
sequence-specific DNA binding
protein self-association
transcription regulatory region DNA binding
MADS box domain binding