286758

• Gene Symbol: Gnas
• Gene Name: GNAS complex locus
• Gene Aliases: Gnas1, Gnpas, Nesp55
• Chromosome Location: Chr.3: 172374957 - 172434988 on Build Rnor_6.0
• UniGene ID: Rn.127731
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gnas
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019132.1	NP_062005.1		263
GenBank mRNA	BC061967.1	-		225
	BC158589.1	-		118	9099119
	DQ120475.1	-		112
	DQ120476.1	-		112
	FQ212511.1	-		90
	L10326.1	-	1	99
	M12673.1	-		327
	M17525.1	-		263

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_080426, NM_001077489, NM_000516, NM_001077488, X07036, and others.
This siRNA also targets the following transcripts in Mouse: NM_001077510, NM_201616, Y00703, BC013840, AK147051, and others.

Panther Classification:

Molecular Function -

heterotrimeric G-protein

Gene Ontology Categories:

Process(es)

skeletal system development
tissue homeostasis
positive regulation of protein phosphorylation
endochondral ossification
energy reserve metabolic process
DNA methylation
regulation of transcription from RNA polymerase II promoter
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway
sensory perception of chemical stimulus
metabolic process
post-embryonic development
positive regulation of sodium ion transport
positive regulation of cAMP biosynthetic process
embryonic hindlimb morphogenesis
multicellular organism growth
negative regulation of renal sodium excretion
negative regulation of multicellular organism growth
post-embryonic body morphogenesis
response to drug
skin development
positive regulation of cAMP-mediated signaling
positive regulation of osteoblast differentiation
positive regulation of osteoclast differentiation
negative regulation of blood pressure
developmental growth
embryonic cranial skeleton morphogenesis
cognition
cartilage development
calcium ion homeostasis
bone development
hair follicle placode formation
platelet aggregation
response to parathyroid hormone
cellular response to prostaglandin E stimulus
genetic imprinting
cellular response to catecholamine stimulus
adenylate cyclase-activating adrenergic receptor signaling pathway

Function(s)

G-protein alpha-subunit binding
GTPase activity
signal transducer activity
insulin-like growth factor receptor binding
protein binding
GTP binding
protein domain specific binding
G-protein beta-subunit binding
G-protein beta/gamma-subunit complex binding
beta-2 adrenergic receptor binding
D1 dopamine receptor binding
mu-type opioid receptor binding
ionotropic glutamate receptor binding
alpha-tubulin binding
metal ion binding
corticotropin-releasing hormone receptor 1 binding