287387

• Gene Symbol: Gnas
• Gene Name: GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
• Gene Aliases: 5530400H20Rik, A930027G11Rik, C130027O20Rik, GPSA, GSP, Galphas, Gnas1, Gnasxl, Gsa, Nesp, Nespl, Oed-Sml, Oedsml, P1, P2, P3, PHP1A, PHP1B, POH
• Chromosome Location: Chr.2: 174283444 - 174346744 on Build GRCm38
• UniGene ID: Mm.125770
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gnas
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001077507.1	NP_001070975.1	2	2376
	NM_001077510.2	NP_001070978.1	2	363
	NM_010309.3	NP_034439.2	2	2376
	NM_019690.2	NP_062664.2	3	1081
	NM_022000.2	NP_068840.2	3	1081
	NM_201616.1	NP_963910.1	2	363
	NM_201618.1	NP_963912.1	2	2376
GenBank mRNA	AF107847.1	-	3	1085
	AF107848.1	-	3	1079
	AF116268.1	-	2	1305
	AF125259.1	-	2	478
	AF175305.1	-	3	1056
	AJ010163.1	-	3	1047
	AK078037.1	-	2	377
	AK085136.1	-	1	1134
	AK132636.1	-	2	464
	AK147051.1	-	2	361
	AK159563.1	-	2	364
	AK168996.1	-	2	334
	AK197380.1	-	2	33
	AY519501.1	-	2	2376
	AY519502.1	-	2	2376
	AY519504.1	-	3	2471
	AY682719.1	-	3	69
	BC013824.1	-	2	176
	BC013840.1	-	2	176
	BC034446.1	-	2	458
	BC038067.1	-	3	375
	BC061496.1	-	2	347
	BC062654.1	-	3	2518
	BC080816.1	-	2	352
	BC092055.1	-	2	167
	BC106133.1	-	2	169
	BF468141.1	-	2	355
	BY718446.1	-	2	137
	M13964.1	-	2	166
	Y00703.1	-	2	175

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001159653, NM_001024823, NM_019132, NM_021845, NM_001159656, and others.

Panther Classification:

Molecular Function -

heterotrimeric G-protein

Gene Ontology Categories:

Process(es)

skeletal system development
tissue homeostasis
positive regulation of protein phosphorylation
endochondral ossification
energy reserve metabolic process
DNA methylation
regulation of transcription from RNA polymerase II promoter
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway
sensory perception of chemical stimulus
post-embryonic development
regulation of signal transduction
positive regulation of sodium ion transport
positive regulation of cAMP biosynthetic process
embryonic hindlimb morphogenesis
multicellular organism growth
negative regulation of renal sodium excretion
negative regulation of multicellular organism growth
post-embryonic body morphogenesis
response to drug
positive regulation of GTPase activity
skin development
positive regulation of cAMP-mediated signaling
positive regulation of osteoblast differentiation
positive regulation of osteoclast differentiation
negative regulation of blood pressure
developmental growth
embryonic cranial skeleton morphogenesis
cognition
cartilage development
calcium ion homeostasis
bone development
hair follicle placode formation
platelet aggregation
response to parathyroid hormone
cellular response to prostaglandin E stimulus
genetic imprinting
cellular response to catecholamine stimulus
adenylate cyclase-activating adrenergic receptor signaling pathway

Function(s)

nucleotide binding
G-protein alpha-subunit binding
GTPase activity
signal transducer activity
insulin-like growth factor receptor binding
protein binding
GTP binding
guanyl nucleotide binding
protein domain specific binding
G-protein beta-subunit binding
G-protein beta/gamma-subunit complex binding
beta-2 adrenergic receptor binding
D1 dopamine receptor binding
mu-type opioid receptor binding
ionotropic glutamate receptor binding
alpha-tubulin binding
metal ion binding
corticotropin-releasing hormone receptor 1 binding